The game prominently features illustrations straight from the manga, some with unique touches just for the game.
Araki patterned most of Midler's revised design from Yukako Yamagishi from Diamond is Unbreakable, having similar body builds. Hirohiko Araki served as a consultant for the game and created exclusive pieces of artwork for its promotion and packaging most notably, he developed from scratch a new character design for Midler, since Capcom was interested in using her in the game and she had been only vaguely shown in the original manga.
It also features many of the gameplay mechanics seen on previous Capcom fighting games, such as the use of power gauges for super moves, as well as a brand new Stand Mode, where a character's Stand can be summoned or dismissed at will by the player, resulting in variations on the character's move list and abilities. The game combines Capcom's trademark anime-inspired graphics, as seen in the Darkstalkers W series, with the colorful characters and events of Hirohiko Araki's creation, resulting in a highly stylized and detailed visual style. The games were developed by the same team responsible for the Street Fighter III series.